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L.R.
Verified Customer
Glia has been such a relaxer for me, both day and night. I have the best sleep, and I have the calmest mood during the day on Glia. I tend to get overstimulated during the day and Glia just balances that right out.

ProdromeGlia™ (Softgels)

ProdromeGlia™ (Softgels)

 (5745 Reviews)
Regular price $92.50
Regular price $92.50 Sale price $99.00
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Omega-9 Plasmalogen Oil

Size: 60 Softgels

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Brain and nerve support helps bring calm and focus to the body and mind. 

Discover the power of advanced neurological support with ProdromeGLIA™, a revolutionary supplement scientifically designed by Dr. Dayan Goodenowe. Built on over two decades of dedicated plasmalogen research, this omega-9 (oleic acid) plasmalogen precursor is formulated to help restore and optimize cellular function in critical areas such as brain white matter, myelin, and heart membranes.

ProdromeGLIA™ omega-9 plasmalogen precursors are the most extensively researched and only patented and validated method to restore omega-9 plasmalogens. These precursors may help prevent demyelination and neurodegeneration and reduce lipid peroxidation.

Ingredients

Omega-9 Plasmalogen Oil (ProdromeGlia™)

Other Ingredients: Softgel capsule (gelatin derived from bovine, glycerol, purified water).

(Free of milk, fish, egg, shellfish, peanuts, treenuts, wheat, yeast, gluten, soy)

How To Use

Most Common: Take 2 softgels* daily or as directed by your health care professional.

Loading Dose: Take 4 to 8 softgels daily for 1 to 3 months.

*2 soft gels = 1 mL

Kindly note that our team is unable to offer detailed dosing instructions or specific protocols. Please direct these questions to a health professional.

When should I take it?: We recommend taking ProdromeGlia™ in the evening as it can have a calming effect.

WARNING

Keep out of reach of children. Do not use if the safety seal is broken or missing.

If you are pregnant, nursing, taking medication(s), or have medical conditions, contact your healthcare professional prior to using this product.

STORAGE

Store at room temperature in a cool, dry place before and after opening.

 

Connect with a Plasmalogen Provider

Prodrome Science, in collaboration with Dr. Goodenowe Research, has been at the forefront of training healthcare practitioners in the use of advanced, research-grade tools to measure and restore biochemical health.

Through this education, providers learn how to optimize plasmalogen levels as a foundational strategy for longevity and neurological resilience.

The most dedicated practitioners are invited to join the Elite Practitioner Program—a rigorous, immersive curriculum that builds deep expertise in the BioMetrix™ NeuroMRI, BioMetrix™ BioScan, and Neurological Plasmalogen Optimization protocols.

How Do Plasmalogens Work?

Plasmalogens are the matrix of the cell membranes and are the essential phospholipids that play a critical structural and functional role in the brain cell. They help maintain the proper fluidity and curvature of neuronal membranes. (Prodrome Glia™) help to ensure the correct compaction, insulation, and stability of myelin membranes, while DHA plasmalogens (Prodrome Neuro™) support neurotransmitter release, and modulate the activation of key receptors involved in neuronal survival and plasticity.³ They also reduce inflammatory signaling (e.g., by inhibiting NF-κB pathways), protecting oligodendrocytes and promoting remyelination.⁴Learn more about plasmalogens and the clinical benefits of plasmalogen optimization here.

Plasmalogens are critical to all cells.

Brain

Plasmalogens solidify and amplify the signals between neurons to optimize physical and cognitive performance.

Blood

People with high blood plasmalogens were 80% less likely to experience dementia and are proven to live longer.

Cell Walls

Plasmalogens are the building blocks of healthy cells, including building and strengthening the myelin sheath inneuronal cells.

Lungs

Plasmalogens promote and stabilize nonlamellar hexagonal phase structure and have significant antioxidant effects.

Heart

Plasmalogens strengthen the heart muscle by reinforcing the cellular structure and function and preventing premature oxidation.

Hair & Nails

Plasmalogens in nail beds and hair follicles allow richer & thicker hair and healthier & faster-growing nails.

Aging

Antioxidant free radical that acts as the body’s first line of defense against oxidation, disease and aging.

Eyes

Plasmalogens are vitally important in the membranes of neuronal tissues that link the brain and the retina. The higher the plasmalogen levels, the lower the risk of glaucoma.

  • Made in the USA

    Virtually all of our products are made in the USA.

  • GMP Standards

    All our products adhere to strict GMP quality standards.

  • Clinically Proven

    Scientifically designed to correct deficiencies in key molecules.

    The Prodrome Brand Promise

    The Prodrome Brand Promise

    Every Prodrome Science product was created with a singular purpose. And that purpose is YOU. When you see the Dr. Goodenowe approved seal you can trust that this product is the result of a lifetime of acquired knowledge in biochemical mechanisms of health and disease. From the years of research and exhaustive clinical testing to the strict cGMP processes that apply to each step of our product pipeline, our team is dedicated to delivering the best biochemical essentials. Everything that you need and nothing that you don’t. Prodrome Science is a paradigm shift from today’s symptom-based healthcare system. A Prodrome-based health care system optimizes the body’s biochemistry before illness or disease has a chance to take root. Prodrome Science represents a departure from chronic disease treatment to health and vitality restoration—not just living longer, but living better.

    Disclaimer

    Products sold by Prodrome are intended for research, educational, and informational use only and are not intended to diagnose or treat any disease. You should always seek the advice of a physician or other healthcare provider with any questions you have regarding the diagnosis, cure, treatment, mitigation, or prevention of any disease or other medical condition or impairment of status of your health. Prodrome does not provide medical advice. None of the statements in any of our materials have been evaluated by the FDA. Any clinical applications that may be shown, are for educational purposes only. Prodrome products are not validated for clinical use. All international orders are shipped from the U.S. and are intended for Personal Use Only. Customers are responsible for complying with local laws, import regulations, and any applicable duties or restrictions.

    • ★★★★★

      I have been taking this product for 3 months now. My mood is SIGNIFICANTLY improved and overall energy is better. Highly recommend this to anyone with autoimmune issues.

      Maggierose 

    • ★★★★★

      I try never to be without them. They are my number one supplement. Thank you Prodrome for providing such an excellent and helpful product!!!

      Anonymous 

    • ★★★★★

      I was struggling with anxiety and thought I'd try the Glia. I find it lifts my anxiety right away. I had a prescription for Lexapro, but I stopped taking it.

      Margaret

    • ★★★★★

      The first step in helping me sleep! I was already on Melatonin, magnesium and found it difficult to turn off my brain at night, with Glia my brain starts to naturally slow down so that I can REST!

      S.L. 

    • ★★★★★

      I was diagnosed with CIRS 8 years ago. I’ve been supplementing with Prodrome Glia for over a year. In my experience, my brain fog has disappeared and my mental acuity has dramatically improved.

      Lisa Stowell 

    • ★★★★★

      This product is as close to making one's own plasmalogens as possible. Since these are essential and we lose them as we age, this supplement is essential (to maintain you brain) and easy to take.

      Rox

      Dr. Dayan Goodenowe

      Dr. Goodenowe is a PhD neuroscientist, biochemist, synthetic organic chemist, inventor, and clinical research expert. In 1999, he invented and patented a revolutionary ion cyclotron resonance mass spectrometry technology that, for the first time in history, made it possible to comprehensively monitor human biochemistry.

      Using this advanced technology, Dr. Goodenowe analyzed blood samples from tens of thousands of persons of all ages, of all races, and from multiple countries. The biochemistry of healthy persons was compared to persons suffering from disease. A diverse range of over 20 diseases from autism to dementia, and from colon cancer to heart disease was studied. The biochemistry of young versus old, and all-cause mortality was studied. This research led to his discovery that early mortality and each human disease has a biochemical prodrome.

      A biochemical prodrome is a deviation from health that precedes and is predictive of a future adverse health event such as disease or death.

      These discoveries led to an extensive patent portfolio of diagnostic tests for the early detection and screening of diseases such as specific cancers (colon, pancreatic, ovarian, breast, lung, prostate, and many more), autism, multiple sclerosis, Parkinson’s, ALS, Alzheimer’s, dementia, bipolar disease, schizophrenia, unipolar depression, cardiovascular disease, and others. Dr. Goodenowe created the ProdromeSCAN™ blood test which measures all of the key prodrome biomarkers and offers advanced laboratory test interpretation training for health practitioners.

      Harnessing the Power of Prodrome Science

      Dr. Goodenowe’s discovery of disease prodromes also revealed an opposite truth: people who maintained optimal biochemical health had an extremely low risk of disease – they had biochemical prodromes of health and longevity. The mission of Prodrome Science is to enable each and every person to attain biochemical prodromes of health using scientifically-validated, targeted biochemical nutrition.

      Biochemical prodromes of disease are detectable years in advance of disease symptoms. By converting disease prodromes into health prodromes we can prevent future diseases — a victory with no battle.

      The most devastating negative health prodrome discovered by Dr. Goodenowe was a deficiency in a critical group of lipids called plasmalogens. Dr. Goodenowe discovered that plasmalogen deficiencies are linked to numerous diseases such as Alzheimer’s, autism, multiple sclerosis, most cancers, and early death.

      There is no viable dietary source of plasmalogens to restore plasmalogen deficiencies. Dr. Goodenowe was the first to design, invent, patent, and develop targeted plasmalogen precursors capable of restoring plasmalogens in all cells of the body. Dr. Goodenowe’s plasmalogen precursors have been extensively studied in preclinical and clinical research and are now available as dietary supplements – ProdromeNEURO™ and ProdromeGLIA™. Blood plasmalogen levels can be measured using Dr. Goodenowe’s ProdromeSCAN™ blood test.

      The Prodrome Brand Promise

      Every Prodrome Science product was created with a singular purpose. And that purpose is YOU. When you see the Dr. Goodenowe approved seal you can trust that this product is the result of a lifetime of acquired knowledge in biochemical mechanisms of health and disease. From the years of research and exhaustive clinical testing to the strict cGMP processes that apply to each step of our product pipeline, our team is dedicated to delivering the best biochemical essentials. Everything that you need and nothing that you don’t.The difference is in every bottle.

      Customer Reviews

      I take Prodrome Neuro daily and feel confident that I am protecting and nourishing my cells, which is so important as we age. I am extremely grateful that this product exists!

      Gail B. 

      VERIFIED PURCHASE

      The ProdromeGlia oil has a pleasant sunflower oil taste making it easy to take. The benefits I've experienced is a calming effect allowing me to focus on work during the day and relax in the evening. I've also noticed the added benefit of my skin looking better along with my hair and nails.

      Keri H.

      VERIFIED PURCHASE

      This product is amazing for any inflammatory issues. Use it on myself and our dogs and have had amazing results!

      James

      VERIFIED PURCHASE

      I have been taking this supplement for the past three years, almost 70, still working and feel great despite the fact that I have a gene for Alzheimer’s Disease. I strongly recommend it along with a healthy diet and lifestyle!

      Diane Larkin

      VERIFIED PURCHASE

      I've been searching for something like this for awhile and I have found this to be one of the most effective ways to have brain clarity and support my gut as well! over all my health and wellness in high stress work environments has been aided with this!

      Michael

      VERIFIED PURCHASE

      I take Prodrome Neuro daily and feel confident that I am protecting and nourishing my cells, which is so important as we age. I am extremely grateful that this product exists!

      Gail B. 

      VERIFIED PURCHASE

      The ProdromeGlia oil has a pleasant sunflower oil taste making it easy to take. The benefits I've experienced is a calming effect allowing me to focus on work during the day and relax in the evening. I've also noticed the added benefit of my skin looking better along with my hair and nails.

      Keri H.

      VERIFIED PURCHASE

      This product is amazing for any inflammatory issues. Use it on myself and our dogs and have had amazing results!

      James

      VERIFIED PURCHASE

      I have been taking this supplement for the past three years, almost 70, still working and feel great despite the fact that I have a gene for Alzheimer’s Disease. I strongly recommend it along with a healthy diet and lifestyle!

      Diane Larkin

      VERIFIED PURCHASE

      I've been searching for something like this for awhile and I have found this to be one of the most effective ways to have brain clarity and support my gut as well! over all my health and wellness in high stress work environments has been aided with this!

      Michael

      VERIFIED PURCHASE

      FAQS

      Why do I need Plasmalogens?

      Our bodies naturally produce plasmalogens, unique lipid molecules essential for the proper functioning of nerve, heart, lung, eye, and kidney cells. However, as we age or face health issues, our ability to produce these critical molecules diminishes. This decline can lead to a host of issues, from cognitive impairment to weakened overall bodily function.

      Diet alone can't solve this problem because plasmalogens are degraded in the gut.

      That's where ProdromeGlia™ steps in. It delivers these vital molecules directly to where they are needed most, allowing you to maintain optimal health and vitality.

      Who should take ProdromeGlia™?

      ProdromeGlia™ is a dietary supplement designed to support myelin health and brain function. It may be beneficial for:

      • Individuals looking to support myelin integrity: Myelin is essential for nerve function, and maintaining its health is important.
      • Those seeking brain health support: Myelin structure and function can be influenced by various factors, including aging and lifestyle.
      • Individuals managing stress: Prolonged stress may impact the cells that help maintain myelin, such as oligodendrocytes and Schwann cells.
      • Aging populations: Plasmalogens, critical components of myelin, naturally decline over time.
      • Those taking ProdromeNeuro™: ProdromeGlia™ is often used alongside ProdromeNeuro™ to provide a more comprehensive approach to brain health, with a focus on myelin (white matter) support.

         _____________________

        This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare professional before starting any new supplement.

      What is the difference between ProdromeGlia™ and ProdromeNeuro™?

      ProdromeNeuro™ and ProdromeGlia™ are both dietary supplements that are synthetically pure plasmalogen precursors. The difference between the two lies in their fatty acid composition and targeted area of effect within the body.

      ProdromeGlia™ is an omega-9 (oleic acid) plasmalogen precursor.  It contains the plasmalogen building blocks for glial cells that make up brain white matter. Glia are cells that surround, support, and protect neurons. These plasmalogens commonly decrease with inflammation. 

      ProdromeNeuro™ is an omega-3 (DHA) plasmalogen precursor. It contains the plasmalogen building blocks for neurons that make up brain gray matter. Neurons are cells that process and transmit information in the body. These plasmalogens commonly become deficient with age. 

      Both plasmalogen precursors are manufactured in a cGMP facility in Temecula, CA, USA

      How is ProdromeGlia™ made?

      ProdromeGlia is made using a patented process that combines purified oleic acid with a synthesized plasmalogen precursor backbone to create a stable and bioavailable oil.

      What happens in our lab:

      • Purifying Oleic Acid: Oleic acid (an omega-9 fatty acid) is extracted from organic high oleic acid sunflower meal. The sunflower oil is broken down to separate the oleic acid from its glycerol backbone. The oleic acid is then washed and purified to remove trace metals, organic contaminants, and microbiological impurities.
      • Synthesizing the Plasmalogen Precursor Backbone: Unlike animal-derived sources, the plasmalogen precursor backbone is created from scratch in a pure form.
      • Combining the Components: The purified oleic acid is attached to the plasmalogen precursor, forming ProdromeGlia oil.
      • Final Purification & Packaging: Before bottling or encapsulation, the oil undergoes further purification to remove oxygen and water molecules, ensuring maximum purity and resistance to oxidation.

      ____________________

      All steps are performed in our own cGMP-certified manufacturing facility to ensure quality and safety.

      *The finished product does not contain any sunflower oil—only the purified oleic acid

      What is Myelin and What Does It Have to Do With Plasmalogens?

      Your nervous system is like a high-speed internet network, with nerve fibers (axons) acting as cables that carry signals between your brain, spinal cord, and the rest of your body. These signals control everything from movement and reflexes to thoughts and memory.

      Myelin is a protective coating that wraps around these nerve fibers—similar to the insulation on electrical wires. Without this insulation, signals can get lost or slow down, leading to problems with movement, thinking, or even basic body functions.

      ______________

      Why is Myelin Important?

      • Keeps signals strong and fast – Without myelin, nerve signals weaken or get disrupted, like a bad Wi-Fi connection.
      • Protects nerves from damage – Myelin shields nerve fibers from harmful stress and wear.
      • Helps your brain and body communicate – Every time you move, think, or feel something, nerve impulses travel through these myelin-covered pathways.


      The Role of Plasmalogens in Myelin

      Myelin is made up of special fats called plasmalogens, which help keep it strong and functional. Your body relies on specific cells—oligodendrocytes in the brain and Schwann cells in the rest of the nervous system—to build and repair myelin. These cells produce omega-9 plasmalogens, which are essential for myelin health.


      ProdromeGlia™ provides omega-9 plasmalogen precursors, supporting the cells that maintain and repair myelin—helping keep your nerve signals clear, fast, and reliable.